PT-141 (Bremelanotide) Reconstitution
How to mix PT-141 (Bremelanotide) and read the exact units to draw. Enter your vial size and bacteriostatic water below for the concentration and dose on a U-100 insulin syringe.
How to reconstitute PT-141 (Bremelanotide)
- Swab the rubber stopper of the PT-141 (Bremelanotide) vial and the bacteriostatic water vial with an alcohol wipe.
- Draw 2 ml of bacteriostatic water into a syringe.
- Inject it slowly down the inside wall of the PT-141 (Bremelanotide) vial, not directly onto the powder.
- Swirl gently until the powder fully dissolves. Do not shake. Shaking can damage the peptide.
- No stability data exists for reconstituted PT-141, because the approved product is a solution rather than a powder.
PT-141 (Bremelanotide) concentration by water volume
PT-141 (Bremelanotide) is commonly supplied in 10 mg vials. The concentration depends only on how much bacteriostatic water you add. More water lowers the concentration and makes small doses easier to measure.
| BAC water added | Concentration | Per 1 unit |
|---|---|---|
| 1 ml | 10,000 mcg/ml | 100 mcg |
| 2 ml | 5,000 mcg/ml | 50 mcg |
| 3 ml | 3,333.3 mcg/ml | 33.3 mcg |
PT-141 (Bremelanotide) units to draw
At 5,000 mcg/ml (a 10 mg vial in 2 ml of bacteriostatic water), here is the draw for doses across the range PT-141 (Bremelanotide) is typically used at. Change any number in the calculator above for your own vial.
| Dose | Units to draw | Volume |
|---|---|---|
| 500 mcg | 10 units | 0.10 ml |
| 750 mcg | 15 units | 0.15 ml |
| 1 mg | 20 units | 0.20 ml |
| 1.25 mg | 25 units | 0.25 ml |
| 1.75 mg | 35 units | 0.35 ml |
PT-141 (Bremelanotide) dosing
The FDA-approved dose is 1.75 mg by subcutaneous injection, taken as needed at least 45 minutes before anticipated sexual activity. The label caps use at one dose per 24 hours and no more than eight doses per month. It is an on-demand product, not a daily one, which fits its brain-level, arousal-timing mechanism. Enter your own vial size, water volume, and target dose in the calculator above to convert any PT-141 (Bremelanotide) protocol into exact insulin-syringe units. For the full profile, see the PT-141 (Bremelanotide) compound page.
Storing reconstituted PT-141 (Bremelanotide)
No stability data exists for reconstituted PT-141, because the approved product is a solution rather than a powder. Vyleesi itself is stored at or below 25 degrees C, not frozen, protected from light. For a reconstituted research vial, 2 to 8 degrees C protected from light is convention only and is not label-derived.
Vyleesi is not supplied as a vial you reconstitute. It ships as a single-dose prefilled autoinjector containing 1.75 mg bremelanotide in 0.3 ml of ready-to-inject solution, so the vial size and water volume here are research-supplier convention rather than label values. The 1.75 mg figure is a label dose for premenopausal women with acquired, generalised HSDD, not a general-purpose dose. The label warns of transient blood pressure increases and heart rate decreases after each dose, and limits use to one dose in 24 hours and eight doses per month.
The dose range above comes from approved prescribing information for PT-141 (Bremelanotide).
The math
- Concentration (mcg/ml) = vial size in mg × 1,000 ÷ bacteriostatic water in ml.
- Volume for your dose (ml) = dose in mcg ÷ concentration.
- Units to draw = volume in ml × 100 on a U-100 insulin syringe.
Prefer a full workspace? The peptide dosage & reconstitution calculator adds blend, converter, half-life, and titration tools.
PT-141 (Bremelanotide) reconstitution FAQ
Draw 2 ml of bacteriostatic water into a syringe, inject it slowly down the inside wall of the PT-141 (Bremelanotide) vial, and swirl gently until the powder dissolves. Do not shake. The concentration is the vial size in mg times 1,000, divided by the millilitres you added.
2 ml for a 10 mg vial gives 5,000 mcg/ml. More liquid makes small doses easier to measure accurately. The calculator shows the concentration for any volume you choose.
Units to draw equals your dose in mcg divided by the concentration in mcg/ml, times 100 on a U-100 insulin syringe. At 5,000 mcg/ml, a 1 mg dose is 20 units.
No stability data exists for reconstituted PT-141, because the approved product is a solution rather than a powder. Vyleesi itself is stored at or below 25 degrees C, not frozen, protected from light. For a reconstituted research vial, 2 to 8 degrees C protected from light is convention only and is not label-derived.
References
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Download the appEducational information only. This is not medical advice. Peptide AI is an informational and tracking platform. Everything on this page is for general education. It is not a substitute for professional medical advice and is not a recommendation to use any compound. Many peptides listed here are research compounds the FDA has not approved for human use. Talk to a qualified, licensed healthcare provider before you start, change, or stop any protocol.