Tesamorelin Reconstitution

How to reconstitute Tesamorelin

1. Swab the rubber stopper of the Tesamorelin vial and the sterile water for injection vial with an alcohol wipe.
2. Draw 0.5 ml of sterile water for injection into a syringe.
3. Inject it slowly down the inside wall of the Tesamorelin vial, not directly onto the powder.
4. Swirl gently until the powder fully dissolves. Do not shake. Shaking can damage the peptide.
5. Use EGRIFTA SV immediately after reconstitution.

Tesamorelin concentration by water volume

Tesamorelin is commonly supplied in 2 mg vials. The concentration depends only on how much bacteriostatic water you add. More water lowers the concentration and makes small doses easier to measure.

Tesamorelin units to draw

At 4,000 mcg/ml (a 2 mg vial in 0.5 ml of bacteriostatic water), here is the draw for doses across the range Tesamorelin is typically used at. Change any number in the calculator above for your own vial.

Tesamorelin dosing

The original FDA-approved dose is 2 mg by subcutaneous injection once daily. A later single-vial formulation (Egrifta SV) uses 1.4 mg daily with simpler preparation, and a newer weekly-reconstitution formulation has also been approved to reduce daily burden. All of this is for the approved HIV-lipodystrophy indication; off-label body-composition use does not have an established, validated protocol. Enter your own vial size, water volume, and target dose in the calculator above to convert any Tesamorelin protocol into exact insulin-syringe units. For the full profile, see the Tesamorelin compound page.

Storing reconstituted Tesamorelin

Use EGRIFTA SV immediately after reconstitution. Do not refrigerate and do not freeze the mixed solution, and discard any unused portion. This is the opposite of ordinary peptide handling. Store unreconstituted vials at 20 to 25 degrees C in the original carton, protected from light. EGRIFTA WR differs again: it is stored reconstituted at 20 to 25 degrees C and discarded 7 days after mixing.

The only compound here with a current FDA label. Reconstitution differs from the generic case: 0.5 ml of Sterile Water for Injection supplied in the kit, not bacteriostatic water, rolled gently for 30 seconds rather than shaken. Three formulations exist (EGRIFTA, EGRIFTA SV, EGRIFTA WR) with different vial strengths, volumes, and storage rules, so match the instructions to the product in your hand.

The dose range above comes from approved prescribing information for Tesamorelin.

The math

• Concentration (mcg/ml) = vial size in mg × 1,000 ÷ bacteriostatic water in ml.
• Volume for your dose (ml) = dose in mcg ÷ concentration.
• Units to draw = volume in ml × 100 on a U-100 insulin syringe.

Prefer a full workspace? The peptide dosage & reconstitution calculator adds blend, converter, half-life, and titration tools.

Tesamorelin reconstitution FAQ

References

• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3d783378-b02d-4f19-99dd-0fc91a042224
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/022505s020lbl.pdf