Metabolic & Weight

Survodutide Reconstitution

How to mix Survodutide and read the exact units to draw. Enter your vial size and bacteriostatic water below for the concentration and dose on a U-100 insulin syringe.

How to reconstitute Survodutide

  1. Swab the rubber stopper of the Survodutide vial and the bacteriostatic water vial with an alcohol wipe.
  2. Draw 1 ml of bacteriostatic water into a syringe.
  3. Inject it slowly down the inside wall of the Survodutide vial, not directly onto the powder.
  4. Swirl gently until the powder fully dissolves. Do not shake. Shaking can damage the peptide.
  5. No stability data has been published for reconstituted survodutide.

Survodutide concentration by water volume

Survodutide is commonly supplied in 10 mg vials. The concentration depends only on how much bacteriostatic water you add. More water lowers the concentration and makes small doses easier to measure.

BAC water addedConcentrationPer 1 unit
1 ml10,000 mcg/ml100 mcg
2 ml5,000 mcg/ml50 mcg
3 ml3,333.3 mcg/ml33.3 mcg

Survodutide units to draw

At 10,000 mcg/ml (a 10 mg vial in 1 ml of bacteriostatic water), here is the draw for doses across the range Survodutide is typically used at. Change any number in the calculator above for your own vial.

DoseUnits to drawVolume
600 mcg6 units0.06 ml
2.4 mg24 units0.24 ml
3.6 mg36 units0.36 ml
4.8 mg48 units0.48 ml
6 mg60 units0.60 ml

Survodutide dosing

There is no approved dose because survodutide is not an approved drug. In trials it is given as a once-weekly subcutaneous injection, titrated up gradually over several weeks to limit gastrointestinal side effects, in the same way other incretin drugs are ramped. Any dosing figures come from clinical protocols, not a label, and it is only legitimately available inside a trial. Do not treat trial numbers as instructions. Enter your own vial size, water volume, and target dose in the calculator above to convert any Survodutide protocol into exact insulin-syringe units. For the full profile, see the Survodutide compound page.

Storing reconstituted Survodutide

No stability data has been published for reconstituted survodutide. Refrigerate at 2 to 8 degrees C and protect from light. Stability duration is unknown and is not estimated here.

Not approved. These are trial doses, not a weekly ladder. Survodutide requires unusually long titration because of its glucagon-receptor activity: phase 2 escalated over 16 to 20 weeks. Reading the five doses above as consecutive weeks would be badly wrong. Phase 3 SYNCHRONIZE-1 used 3.6 mg and 6.0 mg maintenance.

The dose range above comes from published clinical trials. Survodutide is not FDA-approved for this use.

The math

Prefer a full workspace? The peptide dosage & reconstitution calculator adds blend, converter, half-life, and titration tools.

Survodutide reconstitution FAQ

How do you reconstitute Survodutide?

Draw 1 ml of bacteriostatic water into a syringe, inject it slowly down the inside wall of the Survodutide vial, and swirl gently until the powder dissolves. Do not shake. The concentration is the vial size in mg times 1,000, divided by the millilitres you added.

How much bacteriostatic water do I add to Survodutide?

1 ml for a 10 mg vial gives 10,000 mcg/ml. More liquid makes small doses easier to measure accurately. The calculator shows the concentration for any volume you choose.

How many units of Survodutide do I draw?

Units to draw equals your dose in mcg divided by the concentration in mcg/ml, times 100 on a U-100 insulin syringe. At 10,000 mcg/ml, a 3.6 mg dose is 36 units.

How do you store reconstituted Survodutide?

No stability data has been published for reconstituted survodutide. Refrigerate at 2 to 8 degrees C and protect from light. Stability duration is unknown and is not estimated here.

References

Track Survodutide in Peptide AI

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Educational information only. This is not medical advice. Peptide AI is an informational and tracking platform. Everything on this page is for general education. It is not a substitute for professional medical advice and is not a recommendation to use any compound. Many peptides listed here are research compounds the FDA has not approved for human use. Talk to a qualified, licensed healthcare provider before you start, change, or stop any protocol.