ARA-290 Reconstitution

How to reconstitute ARA-290

1. Swab the rubber stopper of the ARA-290 vial and the bacteriostatic water vial with an alcohol wipe.
2. Draw 1 ml of bacteriostatic water into a syringe.
3. Inject it slowly down the inside wall of the ARA-290 vial, not directly onto the powder.
4. Swirl gently until the powder fully dissolves. Do not shake. Shaking can damage the peptide.
5. Keep the lyophilised powder at 2 to 8 degrees C, or -20 degrees C for long-term storage.

ARA-290 concentration by water volume

ARA-290 is commonly supplied in 10 mg vials. The concentration depends only on how much bacteriostatic water you add. More water lowers the concentration and makes small doses easier to measure.

ARA-290 units to draw

At 10,000 mcg/ml (a 10 mg vial in 1 ml of bacteriostatic water), here is the draw for doses across the range ARA-290 is typically used at. Change any number in the calculator above for your own vial.

ARA-290 dosing

Clinical trials used subcutaneous injection in the low milligram range, commonly around 4 mg per day over a set number of weeks. Those are study regimens run under supervision, not a validated protocol for self-administration, so treat any figure outside a trial as unproven. Enter your own vial size, water volume, and target dose in the calculator above to convert any ARA-290 protocol into exact insulin-syringe units. For the full profile, see the ARA-290 compound page.

Storing reconstituted ARA-290

Keep the lyophilised powder at 2 to 8 degrees C, or -20 degrees C for long-term storage. Once mixed with bacteriostatic water, refrigerate at 2 to 8 degrees C and use within about 28 to 30 days on preservative grounds. Protect from light and do not freeze the reconstituted solution.

A genuine clinical-trial dose range, unlike most research peptides. 4 mg/day for 28 days produced significant corneal nerve fibre increases and pain reduction in sarcoidosis-associated small fibre neuropathy. In those trials cibinetide was supplied by the sponsor as a prepared sterile solution, not as a vial the patient reconstituted, so the dose transfers but the handling is not manufacturer-validated. ARA-290 is investigational and not approved anywhere.

The dose range above comes from published clinical trials. ARA-290 is not FDA-approved for this use.

The math

• Concentration (mcg/ml) = vial size in mg × 1,000 ÷ bacteriostatic water in ml.
• Volume for your dose (ml) = dose in mcg ÷ concentration.
• Units to draw = volume in ml × 100 on a U-100 insulin syringe.

Prefer a full workspace? The peptide dosage & reconstitution calculator adds blend, converter, half-life, and titration tools.

ARA-290 reconstitution FAQ

References

• https://pmc.ncbi.nlm.nih.gov/articles/PMC3883966/
• https://clinicaltrials.gov/study/NCT02039687